Please Wait...

PIIINP // Intact N-Terminal Propeptide Of Type III Collagen

Biomarker Therapeutic Areas: 
Biomarker Matrices: 

Type III collagen is present in many tissues, such as skin, vascular vessels, ligaments, skeletal muscles, synovial membrane and connective tissues. Type III collagen is an homotrimer of α1 chains encoded by a single gene (Wu et al., 2010). Collagen type III is synthetized as a large procollagen which is subjected to cleavage of its N-terminal peptide and this N-terminal propeptide of collagen type III (PIINP) is released in the blood circulation in direct proportion to newly formed type III collagen. Serum levels of PIIINP are elevated in remodeling tissues and in some diseases with fibrosis (Chalikias and Tziakas, 2015; Cohen, 2012).

Bioclinica Lab employs a manual competitive radioimmunoassay for the measurement of intact PIIINP in serum.

ADDITIONAL RESOURCES

Biomarker Menu

Download MENU

Molecular Marker Laboratory Services

Download Brochure

Alzheimer's Disease Biomarker Lab Expertise

Download Info Sheet

Leader in Clinical Trial
Management Solutions

Successful clinical trials require the ability to see key details and uncover hidden insights. Bioclinica utilizes science and technology to bring clarity to clinical trials, helping companies to develop new life-improving therapies more efficiently and safely.

On the hunt for agile IRT? Ask these 5 Qs to see if it's the real thing. DISCLOSURE: We happen to have such an offe… https://t.co/S6507WxBC8
bioclinica (6 hours ago)
Be among the 1st to hear findings presented in 6 scientific posters in which experts @bioclinica in #Alzheimers… https://t.co/4mBEtFiX0a
bioclinica (2 days ago)
Still using manual methods for trial budget management and forecasting ? A Bioclinica whitepaper shows how purpose-… https://t.co/WlrHLk9B0z
bioclinica (3 days ago)
Swing by @Bioclinica to discuss global site network partnering opportunities during @MySCRS Asia-Pac Site Solutions… https://t.co/m8GHxSmPMY
bioclinica (4 days ago)
Hello from Clinical Operations in Oncology Trials East Coast where Bioclinica is exhibiting & presenting a case stu… https://t.co/oTKJAVddH4
bioclinica (2 weeks ago)
Challenge overcome! Course-correct a clinical trial & collect 400 time points from 40 sites across the US & EU -- a… https://t.co/n3TLrjW3xi
bioclinica (2 weeks ago)

Latest Blogs:

Latin America: Benefit from the Right Partner
Removing Risk from Clinical Trial Management System (CTMS) Implementations
Collaboration Between Clinical Operations and the Logistics and Supply Chain Teams is Key to Trial Success
The Value of Protocol Review
CTMS and RBM: Hot Topics at OCT Nordics in Copenhagen