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Arthritis

Clinical Assessment of Rheumatoid Arthritis: Advantage MRI

  • 0
  • 29 Aug

When designing imaging endpoints for prospective clinical trials in Rheumatoid Arthritis (RA), sponsors often consider the use of Magnetic Resonance Imaging (MRI) for assessment. The utilization of MRI enables the detection of soft tissues for synovial and bone marrow findings in addition to structural damage, providing advanced evaluation of RA.

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Anti Nerve Growth Factor

Monitoring the Joint Safety of Anti-Nerve Growth Factor Drugs

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  • 25 Jul

The March 12, 2012 meeting of the Arthritis Advisory Committee (AAC) of the Food and Drug Administration (FDA) focused on the safety of the anti-nerve growth factor (anti-NGF) drug class. Anti-NGF agents are being developed primarily for the treatment of chronic pain associated with osteoarthritis (OA).

There are three anti-nerve growth factor monoclonal antibodies in clinical development including:

  • Tanezumab (Pfizer) in phase III
  • Fulranumab (Janssen) in phase II
  • REGN475 (Regeneron) in phase II
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MRI in Rheumatoid Arthritis Clinical Trials

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  • 13 Jan

At BioClinica we are fortunate to have a medical affairs group staffed with a medically and scientifically qualified team whose role is to help sponsors with imaging protocol design and how to use emerging technologies to our advantage. Harris Ahmad, M.D.

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