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Authored Publications

Authored Publications


Jacob Elkins, Roland Veltkamp, Joan Montaner, S Claiborne Johnston, Aneesh B Singhal, Kyra Becker, Maarten G Lansberg, Weihua Tang, Ih Chang, Kumar Muralidharan, Sarah Gheuens, Lahar Mehta, Mitchell S V Elkind.  Safety and efficacy of natalizumab in patients with acute ischaemic stroke (ACTION): a randomised, placebo-controlled, double-blind phase 2 trial.  Lancet Neurol March 2017; 16: 217–26.

Mende, Christian W. and Giles, Thomas D. and Bharucha, David B. and Ferguson, William G. and Mallick, Madhuja and Patel, Mehul D.  Efficacy of nebivolol-valsartan single-pill combination in obese and nonobese patients with hypertension.  The Journal of Clinical Hypertension.  DOI: 10.1111/jch.12965.  January 11, 2017.


Noel G McElvaney, MD, Jonathan Burdon, MD, Mark Holmes, MD, Allan Glanville, MD, Peter A B Wark, MD, Philip J Thompson, MD, Paul Hernandez, MD, Jan Chlumsky, MD, Helmut Teschler, MD, Joachim H Ficker, MD, Niels Seersholm, MD, Prof Alan Altraja, MD, Riitta Mäkitaro, MD, Joanna Chorostowska-Wynimko, MD, Marek Sanak, MD, Paul I Stoicescu, MD, Eeva Piitulainen, MD, Oliver Vit, MSc, Marion Wencker, MD, Michael A Tortorici, PhD, Michael Fries, PhD, Jonathan M Edelman, MD, Kenneth R Chapman, MD on behalf of the RAPID Extension Trial Group.  Long-term efficacy and safety of α1 proteinase inhibitor treatment for emphysema caused by severe α1 antitrypsin deficiency: an open-label extension trial (RAPID-OLE).  1 December 2016.  DOI:

Serge Gauthier, MD, Howard H Feldman, MD, Lon S Schneider, MD, Gordon K Wilcock, DM, Giovanni B Frisoni, MD, Jiri H Hardlund, MD, Hans J Moebius, MD, Peter Bentham, MBChB, Karin A Kook, PhD, Damon J Wischik, PhD, Bjoern O Schelter, Charles S Davis, PhD, Roger T Staff, PhD, Luc Bracoud, MSc, Kohkan Shamsi, MD, John M D Storey, Charles R Harrington, PhD, Claude M Wischik, MBBS.  Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial. 15 November 2016. DOI:

Robert R. Ford, Robert W. Ford, Michael O'Neal, Brad S. Kahl, Ling Chen, Mihaela Munteanu & Bruce D. Cheson (2016): Investigator and independent review committee exploratory assessment and verification of tumor response in a non-Hodgkin lymphoma study, Leukemia & Lymphoma, DOI: 10.1080/10428194.2016.1233535.

HK Genant MD, K Engelke PhD, MA Bolognese MD, C Mautalen MD, JP Brown MD, C Recknor MD, S Goemaere MD, T Fuerst PhD, Y-C Yang PhD, A Grauer MD, C Libanati MD.  Effects of Romosozumab Compared with Teriparatide on Bone Density and Mass at the Spine and Hip in Postmenopausal Women with Low Bone Mass.  JBMR, 3 August 2016.

CG Miller, CC Bogado, AJ Nino, AR Northcutt, HJ Yu, EM Lewiecki, G Paul, AR Cobitz, MJ Wooddella, JP Bilezikian, LA Fitzpatrick.  Evaluation of Quantitative Computed Tomography Cortical Hip Quadrant in a Clinical Trial With Rosiglitazone: A Potential New Study Endpoint.  Journal of Clinical Densitometry.

C Tan, K Li, Z Yan, D Yang, S Zhang, HJ Yu, K Engelke, C Miller, D Metaxas.  A Detection-driven and Sparsity-constrained Deformable Model for Fascia Lata Labeling and Thigh Inter-muscular Adipose Quantification.  Computer Vision and Image Understanding.  11 March 2016.

Philip G Conaghan, Mikkel Østergaard, Michael A Bowes, Chunying Wu, Thomas Fuerst, Désirée van der Heijde, Fedra Irazoque-Palazuelos, Oscar Soto-Raices, Pawel Hrycaj, Zhiyong Xie, Richard Zhang, Bradley T Wyman, John D Bradley, Koshika Soma, Bethanie Wilkinson.  Comparing the effects of tofacitinib, methotrexate and the combination, on bone marrow oedema, synovitis and bone erosion in methotrexate-naive, early active rheumatoid arthritis: results of an exploratory randomised MRI study incorporating semiquantitative and quantitative techniques.  Ann Rheum Dis.  25 January 2016.


Coric V, Salloway S, H. van Dyck C, Dubois B, Andreasen N, Brody M, Curtis C, Soininen H, Thein S, Shiovitz T, Pilcher G, Ferris S, Colby S, Kerselaers W, Dockens R, Soares H, Kaplita S, Luo F, Pachai C, Bracoud L, Mintun M, Grill JD, Marek K, Seibyl J, Cedarbaum JM, Albright C, Feldman HH, Berman RM. Targetting Prodromal Alzheimer Disease with Avagacestat A Randomized Clinical Trial.  JAMA Neurol 2015, Sept 28. [Epub ahead of print]

Guttmann CR, Rousset M, Roch JA, Hannoun S, Durand-Dubief F, Belaroussi B, Cavallari M, Rabilloud M, Sappey-Marinier D, Vukusic S, Cotton F. Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study. Multiple Sclerosis Journal. 2015 Sep 11. [Epub ahead of print]

Van Heertum RL, Scarimbolo R, Ford R, Berdougo E, O’Neal M. Companion diagnostics and molecular imaging-enhanced approaches for oncology clinical trials. Drug Design, Development and Therapy 2015:9 5215–5223.

Engelke K, Lang T, Khosla S, Qin L, Zysset P, Leslie WD, Shepherd JA, Shousboe JT. Clinical Use of Quantitative Computed Tomography-Based Advanced Techniques in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part III. J Clin Densitom. 2015 Jul-Sep;18(3):393-407

Zysset P, Qin L, Lang T, Khosla S, Leslie WD, Shepherd JA, Schousboe JT, Engelke K. Clinical Use of Quantitative Computed Tomography-Based Finite Element Analysis of the Hip and Spine in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part II. J Clin Densitom. 2015 Jul-Sep;18(3):359-92.

Engelke K, Lang T, Khosla S, Qin L, Zysset P, Leslie WD, Shepherd JA, Schousboe JT. Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part I. J Clin Densitom. 2015 Jul-Sep;18(3):338-58

Shepherd JA, Schousboe JT, Broy SB, Engelke K, Leslie WD. Executive Summary of the 2015 ISCD Position Development Conference on Advanced Measures From DXA and QCT: Fracture Prediction Beyond BMD. J Clin Densitom. 2015 Jul-Sep;18(3):274-86

Sibon I, Tourdias T, Felix S, Asselineau J, Bracoud L, Vivot A, Rouanet F, Renou P, Orgogozo JM, Dousset V. Magnetisation transfer parameters and stroke outcome. J Clin Neurosci. 2015 Jun;22(6):1012-7.

Krueger D, Libber J, Sanfilippo J, Yu HJ, Horvath B, Miller CG, Binkley N.  A DXA Whole Body Composition Cross-Calibration Experience: Evaluation With Humans, Spine, and Whole Body Phantoms.  J Clin Densitom. 2015 Jun 9. pii: S1094-6950(15)00041-4. doi: 10.1016/j.jocd.2015.04.003. [Epub ahead of print]

Kufner A, Wouters A, Bracoud L, Laage R, Schneider A, Schäbitz W, Hermier M, Thijs V, Fiebach JB, on behalf of the AXIS2 investigators.  Infarct Volume-Based Subgroup Selection in Acute Ischemic Stroke Trials. Stroke, May 2015.

Beck TJ, Fuerst T, Gaither KW, Sutradhar S, Levine AB, Hines T, Yu CR, Williams R, Mirkin S, Chines AA. The effects of bazedoxifene on bone structural strength evaluated by hip structure analysis. Bone. April 23, 2015. Volume 77, Pages 115–119.


Schmidt ME, Chiao P, Klein G, Matthews D, Thurfjell L, Cole PE, Margolin R, Landau S, Foster NL, Mason NS, De Santi S, Suhy J, Koeppe RA, Jagust W; Alzheimer's Disease Neuroimaging Initiative. The influence of biological and technical factors on quantitative analysis of amyloid PET: Points to consider and recommendations for controlling variability in longitudinal data. Alzheimers Dement. 2014 Nov 24. P1-19.

Geiger MJ, Mehta C, Turner JR, Arbet-Engels C, Hantel S, Hirshberg B, Koglin J, Mendzelevski B, Sager PT, Shapiro D, Stewart M, Todaro TG, and Gaydos B. Clinical Development Approaches and Statistical Methodologies to Prospectively Assess the Cardiovascular Risk of New Antidiabetic Therapies for Type 2 Diabetes. 2014 Therapeutic Innovation & Regulatory Science 1-15.

Ahmad H, Berzin TM, Yu HJ, Huang CS, Mishkin DS. Central endoscopy reads in inflammatory bowel disease clinical trials: The role of the imaging core lab. Gastroenterol Rep. 2014 Aug;2(3):201-6.

Hill DL, Schwarz AJ, Isaac M, Pani L, Vamvakas S, Hemmings R, Carrillo MC, Yu P, Sun J, Beckett L, Boccardi M, Brewer J, Brumfield M, Cantillon M, Cole PE, Fox N, Frisoni GB, Jack C, Kelleher T, Luo F, Novak G, Maguire P, Meibach R, Patterson P, Bain L, Sampaio C, Raunig D, Soares H, Suhy J, Wang H, Wolz R, Stephenson D. Coalition Against Major Diseases/European Medicines Agency biomarker qualification of hippocampal volume for enrichment of clinical trials in predementia stages of Alzheimer's disease. Alzheimers Dement. 2014 Jul;10(4):421-9.

Yan Z, Zhang S, Tan C, Qin H, Belaroussi B, Yu HJ, Miller C, Metaxas DN.  Atlas-Based Liver Segmentation and Hepatic Fat-Fraction Assessment for Clinical Trials.  DOI: 10.1016/j.compmedimag.2014.05.012.

Hitt DM, Belabassi Y, Suhy J, Berkman CE, Thompson CM. Chemoenzymatic resolution of rac-malathion. Tetrahedron Asymmetry. 2014 Apr 15;25(6-7):529-533.

Opherk C, Gonik M, Duering M, Malik R, Jouvent E, Hervé D, Adib-Samii P, Bevan S, Pianese L, Silvestri S, Dotti MT, De Stefano N, Liem M, Boon EM, Pescini F, Pachai C, Bracoud L, Müller-Myhsok B, Meitinger T, Rost N, Pantoni L, Oberstein SL, Federico A, Ragno M, Markus HS, Tournier-Lasserve E, Rosand J, Chabriat H, Dichgans M. Genome-Wide Genotyping Demonstrates a Polygenic Risk Score Associated With White Matter Hyperintensity Volume in CADASIL. Stroke. 2014 Feb 27. [Epub ahead of print]


Chabriat H, Maeder P, Gass A, Michel P, Bracoud L, Hennerici MG. Results of the PERFORM magnetic resonance imaging study. J Neurol. 2013 Dec;260(12):3071-6. PMID: 24078046 [PubMed - in process]

Barakos J, Sperling R, Salloway S, Jack C, Gass A, Fiebach JB, Tampieri D, Melançon D, Miaux Y, Rippon G, Black R, Lu Y, Brashear HR, Arrighi HM, Morris KA, Grundman M. MR imaging features of amyloid-related imaging abnormalities. AJNR Am J Neuroradiol. 2013 Oct;34(10):1958-65.

Duering M, Csanadi E, Gesierich B, Jouvent E, Hervé D, Seiler S, Belaroussi B, Ropele S, Schmidt R, Chabriat H, Dichgans M. Incident lacunes preferentially localize to the edge of white matter hyperintensities: insights into the pathophysiology of cerebral small vessel disease. Brain. 2013 Sep;136(Pt 9):2717-26. doi: 10.1093/brain/awt184. Epub 2013 Jul 17. PMID: 23864274

Braddock M, Heilbraun J, Mendzelevski B. Cardiovascular safety and hemodynamic considerations in oncology drug development -- webinar highlights October 10th 2012Expert Opin Drug Saf. 2013 Sep;12(5):783-91. doi: 10.1517/14740338.2013.797407. Epub 2013 May 8. PMID: 23651420

Vingara LK, Yu HJ, Wagshul ME, Serafin D, Christodoulou C, Pelczer I, Krupp LB, Maletic-Savatic M. Metabolomic approach to human brain spectroscopy identifies associations between clinical features and the frontal lobe metabolome in multiple sclerosis. Neuroimage. 2013 Jun 7. PMID: 23751863.

Henriksen K, Wang Y, Sørensen MG, Barascuk N, Suhy J, Pedersen JT, Duffin KL, Dean RA, Pajak M, Christiansen C, Zheng Q, Karsdal MA. An enzyme-generated fragment of tau measured in serum shows an inverse correlation to cognitive function. PLoS One. 2013 May 22;8(5).

Navarro-Compán V, van der Heijde D, Ahmad HA, Miller CG, Wolterbeek R, Landewé R.  Measurement error in the assessment of radiographic progression in rheumatoid arthritis (RA) clinical trials: the smallest detectable change (SDC) revisited.  Ann Rheum Dis. 2013 Apr 20. [Epub ahead of print] PMID: 23606704

Sager P, Heilbraun J, Turner JR, Gintant G, Geiger MJ, Kowey PR, Mansoor GA, Mendzelevski B, Michelson EL, Stockbridge N, Weber MA, White WB. Assessment of drug-induced increases in blood pressure during drug development: report from the Cardiac Safety Research Consortium. Am Heart J. 2013 Apr;165(4):477-88. doi: 10.1016/j.ahj.2013.01.002.

Munzinger U, Guggi T, Kaptein B, Persoon M, Valstar E, Doets HC. A titanium plasma-sprayed cup with and without hydroxyapatite-coating: a randomised radiostereometric study of stability and osseointegration. Hip Int. 2013 Jan 16:0. doi: 10.5301/HIP.2013.10598. [Epub ahead of print] PMID: 23329538

Jouvet JC, Thomas L, Thomson V, Yanes M, Journe C, Morelec I, Bracoud L, Durupt F, Giammarile F, Berthezene Y. Whole-body MRI with diffusion-weighted sequences compared with 18 FDG PET-CT, CT and superficial lymph node ultrasonography in the staging of advanced cutaneous melanoma: a prospective study. J Eur Acad Dermatol Venereol. 2013 Jan 18. doi: 10.1111/jdv.12078. [Epub ahead of print] PMID: 23331931

Navarro-Compán V, Landewé R, Ahmad HA, Miller CG, Xu D, Wolterbeek R, van der Heijde D. Rate of adjudication of radiological progression in rheumatoid arthritis randomized controlled trials depending on preset limits of agreement: a pooled analysis from 15 randomized trials.  Rheumatology (Oxford). 2013 Jan 16. Epub 2013 Jan 16. PMID: 23329683


Wyman BT, Harvey DJ, Crawford K, Bernstein MA, Carmichael O, Cole PE, Crane PK, Decarli C, Fox NC, Gunter JL, Hill D, Killiany RJ, Pachai C, Schwarz AJ, Schuff N, Senjem ML, Suhy J, Thompson PM, Weiner M, Jack CR Jr. Standardization of analysis sets for reporting results from ADNI MRI data. Alzheimer’s Disease Neuroimaging Initiative. Alzheimers Dement. 2012 Oct 27. doi:pii: S1552-5260(12)02379-5. 10.1016/j.jalz.2012.06.004. Epub 2012 Oct 27. PMID: 23110865

Coric V, van Dyck CH, Salloway S, Andreasen N, Brody M, Richter RW, Soininen H, Thein S, Shiovitz T, Pilcher G, Colby S, Rollin L, Dockens R, Pachai C, Portelius E, Andreasson U, Blennow K, Soares H, Albright C, Feldman HH, Berman RM. Safety and Tolerability of the γ-Secretase Inhibitor Avagacestat in a Phase 2 Study of Mild to Moderate Alzheimer Disease. Archives of Neurology 2012 Aug 13:1-12

F. Durand-Dubief, B. Belaroussi, J.P. Armspach, M. Dufour, S. Roggerone, S. Vukusic, S. Hannoun, D. Sappey-Marinier, C. Confavreux and F. Cotton. Reliability of Longitudinal Brain Volume Loss Measurements between 2 Sites in Patients with Multiple Sclerosis: Comparison of 7 Quantification Techniques. American Journal of Neuroradiology. July 2012.

Vellas B, Hampel H, Rougé-Bugat ME, Grundman M, Andrieu S, Abu-Shakra S, Bateman R, Berman R, Black R, Carrillo M, Donohue M, Mintun M, Morris J, Petersen R, Thomas RG, Suhy J, Schneider L, Seely L, Tariot P, Touchon J, Weiner M, Sampaio C, Aisen P; Task Force Participants. Alzheimer's disease therapeutic trials: EU/US Task Force report on recruitment, retention, and methodology. J Nutr Health Aging. 2012 Apr;16(4):339-45.

Sperling R, Salloway S, Brooks DJ, Tampieri D, Barakos J, Fox NC, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Lieberburg I, Arrighi HM, Morris KA, Lu Y, Liu E, Gregg KM, Brashear HR, Kinney GG, Black R, Grundman M. Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis. Lancet Neurol. 2012 Mar;11(3):241-9.

Binkley N, Bolognese M, Sidorowicz-Bialynicka A, Vally T, Trout R, Miller C, Buben CE, Gilligan JP, Krause DS A phase 3 trial of the efficacy and safety of oral recombinant calcitonin: The ORACAL trial. J Bone Miner Res. 2012 Mar 21. 27(8):1821-1829

Mendzelevski, B., J. Ausma, D. O. Chanter, P. Robinson, R. Kerstens, L. Vandeplassche and J. Camm. Assessment of the cardiac safety of prucalopride in healthy volunteers: a randomized, double-blind, placebo-and positive-controlled thorough QT study. Br J Clin Pharmacol. 2012 Feb;73(2):203-9. doi: 10.1111/j.1365-2125.2011.04088.x. PMID: 21848574 [PubMed - indexed for MEDLINE]

Mozley D, Bendtsen C, Zhao B, Schwartz L, Thorn M, Rong Y, Zhang L, Perrone A, Korn R, Buckler A. Measurement of Tumor Volumes Improves RECIST-Based Response Assessments in Advanced Lung Cancer. Translational Oncology (2012) 5, 19–25.

Barbosa, D., Dietenbeck, T., Schaerer, J., D'Hooge, J., Friboulet, D., Bernard, O., 2012. B-spline explicit active surfaces: an efficient framework for real-time 3-D region-based segmentation. IEEE Trans Image Process. 2012 Jan;21(1):241-51. doi: 10.1109/TIP.2011.2161484. PMID: 22186712 [PubMed - indexed for MEDLINE]

Schaerer, J., Fassi, A., Riboldi, M., Cerveri, P., Baroni, G., Sarrut, D. Multi-dimensional respiratory motion tracking from markerless optical surface imaging based on deformable mesh registration. Phys Med Biol. 2012 Jan 21;57(2):357-73. doi: 10.1088/0031-9155/57/2/357. Epub 2011 Dec 14. PMID: 22170786 [PubMed - indexed for MEDLINE]


Schuff N, Suhy J, Goldman R, Xu Y, Sun Y, Truran-Sacrey D, Murthy A. An MRI substudy of a donepezil clinical trial in mild cognitive impairment. Neurobiol Aging. 2011 Dec;32(12):2318.e31-41.

Yu HJ, Christodoulou C, Bhise V, Greenblatt D, Patel Y, Serafin D, Maletic-Savatic M, Krupp LB, Wagshul M. Multiple white matter tract abnormalities underlie cognitive impairment in RRMS. Neuroimage. 2011 Oct 29. PMID: 22062194

Metzler-Baddeley C, Jones DK, Belaroussi B, Aggleton JP, O'Sullivan MJ. Frontotemporal connections in episodic memory and aging: a diffusion MRI tractography study. J Neurosci. 2011 Sep 14;31(37):13236-45. PMID: 21917806

Duering M, Zieren N, Hervé D, Jouvent E, Reyes S, Peters N, Pachai C, Opherk C, Chabriat H, Dichgans M. Strategic role of frontal white matter tracts in vascular cognitive impairment: a voxel-based lesion-symptom mapping study in CADASIL. Brain. 2011 Aug;134(Pt 8):2366-75. Epub 2011 Jul 14

Jack CR Jr, Barkhof F, Bernstein MA, Cantillon M, Cole PE, Decarli C, Dubois B, Duchesne S, Fox NC, Frisoni GB, Hampel H, Hill DL, Johnson K, Mangin JF, Scheltens P, Schwarz AJ, Sperling R, Suhy J, Thompson PM, Weiner M, Foster NL. Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease. Alzheimers Dement. 2011 Jul;7(4):474-485.

Carlson C, Estergard W, Oh J, Suhy J, Jack CR Jr, Siemers E, Barakos J. Prevalence of asymptomatic vasogenic edema in pretreatment Alzheimer's disease study cohorts from phase 3 trials of semagacestat and solanezumab. Alzheimers Dement. 2011 Jul;7(4):396-401.

Weiner MW, Sadowsky C, Saxton J, Hofbauer RK, Graham SM, Yu SY, Li S, Hsu HA, Suhy J, Fridman M, Perhach JL. Alzheimers Dement. Magnetic resonance imaging and neuropsychological results from a trial of memantine in Alzheimer's disease. 2011 Jul;7(4):425-35.

Maeder P, Bracoud L, Chabriat H, Gass A, Michel P, Hennerici M. Design, data management, and population baseline characteristics of the PERFORM magnetic resonance imaging project. Journal of Neurology. 2011 May;258(5):795-803. PMID: 21128081

Aisen PS, Gauthier S, Ferris SH, Saumier D, Haine D, Garceau D, Duong A, Suhy J, Oh J, Lau WC, Sampalis J. Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study). Arch Med Sci. 2011 Feb;7(1):102-11.

Bracoud L, Ahmad H, Brill-Almon E, Chertkoff R. Improving the accuracy of MRI spleen and liver volume measurements: A phase III Gaucher disease clinical trial setting as a model. Blood Cells Mol Dis. 2011 Jan 15;46(1):47-52. Epub 2010 Nov 17. PMID: 21084202


Tourdias T, Renou P, Sibon I, Asselineau J, Bracoud L, Dumoulin M, Rouanet F, Orgogozo JM, Dousset V. Final cerebral infarct volume is predictable by MR imaging at 1 week. AJNR Am J Neuroradiol. 2011 Feb;32(2):352-8. Epub 2010 Oct 21.

Parker J, Wolansky LJ, Khatry D, Geba GP, Molfino NA. Brain Magnetic Resonance Imaging in Adults with Asthma. Contemporary Clinical Trials.

Nonent M, Ben Salem D, Serfaty JM, Buthion V, Pasco-Papon A, Rotaru C, Bressollette L, Papon X, Pachai C, Fortrat JO, Gouny P, Badra A, Berge J, Le Bras Y, Cottier JP, Gauvrit JY, Douek P. Overestimation of moderate carotid stenosis assessed by both Doppler US and contrast enhanced 3D-MR angiography in the CARMEDAS study. J Neuroradiol. 2011 Jul;38(3):148-55. Epub 2010 Aug 21.


O'Sullivan M, Ngo E, Viswanathan A, Jouvent E, Gschwendtner A, Saemann PG, Duering M, Pachai C, Bousser MG, Chabriat H, Dichgans M. Hippocampal volume is an independent predictor of cognitive performance in CADASIL. Neurobiology of Aging. 2009 Jun;30(6):890-7. PMID: 17963999

Sibon I, Ménégon P, Orgogozo JM, Asselineau J, Rouanet F, Renou P, Tourdias T, Pachai C, Chêne G, Dousset V. Inter- and intraobserver reliability of five MRI sequences in the evaluation of the final volume of cerebral infarct. Journal of Magnetic Resonance Imaging. 2009 Jun;29(6):1280-4. PMID: 19472382

Fisher M, Feuerstein G, Howells DW, Hurn PD, Kent TA, Savitz SI, Lo EH; STAIR Group (contributor Ahmad H). Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations. Stroke. 2009 Jun;40(6):2244-50. doi: 10.1161/STROKEAHA.108.541128. Epub 2009 Feb 26. PMID: 19246690

Bogaerts J, Ford R, Sargent D, Schwartz LH, Rubinstein L, Lacombe D, Eisenhauer E, Verweij J, Therasse P, for the RECIST Working Party. Individual Patient Data Analysis to Assess Modifications to the RECIST Criteria. European Journal of Cancer 45 (2009) 248–260.

Ford R, Schwartz L, Dancey J, Dodd LE, Eisenhauer EA, Gwyther S, Rubinstein L, Sargent D, Shankar L, Therasse P, Verweij J. Lessons Learned from Independent Central Review. European Journal of Cancer 45 (2009) 268–247.

Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargente D, Ford R, Dancey J, Arbuck S, Gwyther S, Mooney M, Rubinstein L, Shankar L, Dodd L, Kaplan R, Lacombe D, Verweij J. New Response Evaluation Criteria in Solid Tumours: Revised RECIST Guideline (version 1.1). European Journal of Cancer 45 (2009) 228–247.

Danceya JE, Doddb LE, Ford R, Kapland R, Mooney M, Rubinstein L, Schwartze LH, Shankarb L, Therassef P. Recommendations for the Assessment of Progression in Randomised Cancer Treatment Trials. European Journal of Cancer 45 (2009) 281–289.

Hervé D, Godin O, Dufouil C, Viswanathan A, Jouvent E, Pachaï C, Guichard JP, Bousser MG, Dichgans M, Chabriat H. Three-dimensional MRI analysis of individual volume of Lacunes in CADASIL. Stroke. 2009 Jan;40(1):124-8. PMID: 18948610


O'Sullivan M, Jouvent E, Saemann PG, Mangin JF, Viswanathan A, Gschwendtner A, Bracoud L, Pachai C, Chabriat H, Dichgans M. Measurement of brain atrophy in subcortical vascular disease: a comparison of different approaches and the impact of ischaemic lesions. Neuroimage. 2008 Nov 1;43(2):312-20. PMID: 18722537

Viswanathan A, Godin O, Jouvent E, O'Sullivan M, Gschwendtner A, Peters N, Duering M, Guichard JP, Holtmannspötter M, Dufouil C, Pachai C, Bousser MG, Dichgans M, Chabriat H. Impact of MRI markers in subcortical vascular dementia: A multi-modal analysis in CADASIL. Neurobiology of Aging. 2008 Oct 14. PMID: 18926602

Viswanathan A, Patel P, Rahman R, Nandigam RN, Kinnecom C, Bracoud L, Rosand J, Chabriat H, Greenberg SM, Smith EE. Tissue microstructural changes are independently associated with cognitive impairment in cerebral amyloid angiopathy. Stroke. 2008 Jul;39(7):1988-92. PMID: 18436874

Ford R, Mozley PD. Report of Task Force II: Best Practices in the Use of Medical Imaging Techniques in Clinical Trials. Drug Information Journal, Vol. 42, pp. 515–523, 2008.


Tourdias T, Dousset V, Sibon I, Pele E, Menegon P, Asselineau J, Pachai C, Rouanet F, Robinson P, Chene G, Orgogozo JM. Magnetization transfer imaging shows tissue abnormalities in the reversible penumbra. Stroke. 2007 Dec;38(12):3165-71. PMID: 17962607

Kantor AB, Deng J, Waubant E, Lin H, Becker CH, Lacy JR, Perrone AM, Bennett D, Goelz SE. Identification of short-term pharmacodynamic effects of interferon-beta-1a in multiple sclerosis subjects with broad- based phenotypic profiling. Journal of Neuroimmunology. 2007 Aug;188(1-2):103-16. PMID: 17614141

Viswanathan A, Gschwendtner A, Guichard JP, Buffon F, Cumurciuc R, O'Sullivan M, Holtmannspötter M, Pachai C, Bousser MG, Dichgans M, Chabriat H. Lacunar lesions are independently associated with disability and cognitive impairment in CADASIL. Neurology. 2007 Jul 10;69(2):172-9. PMID: 17620550

Boussel L, Serusclat A, Skilton MR, Vincent F, Bernard S, Moulin P, Saloner D, Douek PC. The reliability of high resolution MRI in the measurement of early stage carotid wall thickening. Journal of cardiovascular magnetic resonance. 2007;9(5):771-6. PMID: 17891614

Vistvanathan, A., Patel, P., Rahman, R., Nandigam, K., Kinnecom, C., Pachai, C., Rosand, J., Chabriat, H., Greenberg, S.M., Smith, E., 2007. Tissue microstructural changes are independently associated with pre-index cognitive impairment in survivors of lobar intracerebral hemorrhage. Annals of neurology 62, S56-S56.


Viswanathan A, Guichard JP, Gschwendtner A, Buffon F, Cumurcuic R, Boutron C, Vicaut E, Holtmannspötter M, Pachai C, Bousser MG, Dichgans M, Chabriat H. Blood pressure and haemoglobin A1c are associated with microhaemorrhage in CADASIL: a two-centre cohort study. Brain. 2006 Sep;129(Pt 9):2375-83. PMID: 16844717

Serfaty JM, Nonent M, Nighoghossian N, Rouhart F, Derex L, Rotaru C, Chirossel P, Thabut G, Guias B, Heautot JF, Gouny P, de la Vega A, Pachai C, Ecochard R, Villard J, Douek PC; CARMEDAS Study Group. Plaque density on CT, a potential marker of ischemic stroke. Neurology. 2006 Jan 10;66(1):118-20. Erratum in: Neurology. 2006 Apr 25;66(8):1288. PMID: 16401860

Finken MJ, Inderson A, Van Montfoort N, Keijzer-Veen MG, van Weert AW, Carfil N, Frölich M, Hille ET, Romijn JA, Dekker FW, Wit JM; Dutch POPS-19 Collaborative Study Group. Lipid profile and carotid intima-media thickness in a prospective cohort of very preterm subjects at age 19 years: effects of early growth and current body composition. Pediatric Research. 2006 Apr;59(4 Pt 1):604-9. PMID: 16549538

Belaroussi B, Milles J, Carme S, Zhu YM, Benoit-Cattin H. Intensity non-uniformity correction in MRI: existing methods and their validation. Med Image Anal. 2006 Apr;10(2):234-46. PMID: 16307900

Zimmerman RD, Maldjian JA, Brun NC, Horvath B, Skolnick BE. Radiologic Estimation of Hematoma Volume in Intracerebral Hemorrhage Trial by CT Scan. AJNR Am J Neuroradiol. 2006 Mar;27(3):666-70. PMID: 16552014

Dawkins KD, Chevalier B, Suttorp MJ, Thuesen L, Benit E, Bethencourt A, Morjaria U, Veldhof S, Dorange C, van Weert A; TRENDS Investigators. Effectiveness of Direct Stenting Without Balloon Predilatation (from the Multilink Tetra Randomised European Direct Stent Study (TRENDS). American Journal of Cardiology. 2006 Feb 1;97(3):316-21. PMID: 16442388

Kelbaek H, Thuesen L, Helqvist S, Kløvgaard L, Jørgensen E, Aljabbari S, Saunamäki K, Krusell LR, Jensen GV, Bøtker HE, Lassen JF, Andersen HR, Thayssen P, Galløe A, van Weert A; SCANDSTENT Investigators. The Stenting Coronary Arteries in Non-stress/benestent Disease (SCANDSTENT) trial. Journal of American College of Cardiology. 2006 Jan 17;47(2):449-55. PMID: 16412876

Reid DM, Mackay I, Wilkinson S, Miller C, Schuette DG, Compston J, Cooper C, Duncan E, Galwey N, Keen R, Langdahl B, McLellan A, Pols H, Uitterlinden A, Riordan JO, Wass JAH, Ralston SH, Bennett ST. Cross-calibration of Dual Energy X-ray densitometers for a large, multi-centre genetic study of osteoporosis. Osteoporos Int. 2006 Jan;17(1):125-32. Epub 2005 Sep 1. PMID: 16136277


Ménégon P, Sibon I, Pachai C, Orgogozo JM, Dousset V. Marchiafava-Bignami disease: diffusion-weighted MRI in corpus callosum and cortical lesions.  Neurology. 2005 Aug 9;65(3):475-7. PMID: 16087921

McClung MR, San Martin J, Miller PD, Civitelli R, Bandeira F, Omizo M, Donley DW, Dalsky GP, Eriksen EF. Opposite Bone Remodeling Effects of Teriparatide and Alendronate in Increasing Bone Mass. Arch Intern Med. 2005 Aug 8-22;165(15):1762-8. PMID: 16087825

Deloire MS, Salort E, Bonnet M, Arimone Y, Boudineau M, Amieva H, Barroso B, Ouallet JC, Pachai C, Galliaud E, Petry KG, Dousset V, Fabrigoule C, Brochet B. Cognitive Impairment as Marker of Diffuse Brain Abnormalities in Early Relapsing Remitting Multiple Sclerosis. Journal of Neurology, Neurosurgery and Psychiatry. 2005 Apr;76(4):519-26. PMID: 15774439

Benoit-Cattin H, Collewet G, Belaroussi B, Saint-Jalmes H, Odet C. The SIMRI project: a versatile and interactive MRI simulator. J Magn Reson. 2005 Mar;173(1):97-115. PMID: 15705518

Cotton F, Euvrard T, Durand-Dubief F, Pachai C, Cucherat M, Ramirez Rozzi F, Bonmartin A, Guihard-Costa AM, Tran Minh VA, Vallee B, Froment JC. Correlation between Cranial Vault Size and Brain Size over Time: Preliminary MRI Evaluation. Journal of Neuroradiology. 2005 Mar;32(2): 131-7. PMID: 15984405


Cotton F, Rozzi FR, Vallee B, Pachai C, Hermier M, Guihard-Costa AM, Froment JC. Cranial sutures and craniometric points detected on MRI. Surg Radiol Anat.  2005 Mar;27(1):64-70. Epub 2004 Oct 29. PubMed ID: 15517262

Kantor AB, Wang W, Lin H, Govindarajan H, Anderle M, Perrone A, Becker C.  Biomarker discovery by comprehensive phenotyping for autoimmune diseases.  Clinical Immunology. 2004 May;111(2):186-95. PMID: 15137951

Nonent M, Serfaty JM, Nighoghossian N, Rouhart F, Derex L, Rotaru C, Chirossel P, Guias B, Heautot JF, Gouny P, Langella B, Buthion V, Jars I, Pachai C, Veyret C, Gauvrit JY, Lamure M, Douek PC; CARMEDAS Study Group.  Concordance rate differences of 3 noninvasive imaging techniques to measure carotid stenosis in clinical routine practice: results of the CARMEDAS multicenter study. Stroke.  2004 Mar;35(3):682-6. PubMed ID: 14764932



Boudraa AO, Dehak SM, Zhu YM, Pachai C, Bao YG, Grimaud J. Automated segmentation of multiple sclerosis lesions in multispectral MR imaging using fuzzy clustering. Comput Biol Med. 2000 Jan;30(1):23-40. PMID: 10695813


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