BioClinica Clinical Trial Studies

BioClinica Studies


Pitale S, Thomas M, Rathi G, Deshmukh V, Kumar P, Reddy S, Shetty N, Kakar A, Babhulkar S, Mody B, Chacko J, Acharya S, Joglekar S, Halbe V, Kravitz BG, Waterhouse B, Nino AJ, Fitzpatrick LA.  A randomized placebo-controlled trial of the efficacy of denosumab in Indian postmenopausal women with osteoporosis.  Indian Journal of Endocrinology and Metabolism.  Jan-Feb 2015.


Gadgeel SM, Gandhi L, Riely GJ, Chiappori AA, West HL, Azada MC, Morcos PN, Lee R, Garcia L, Yu L, Boisserie F, Di Laurenzio L, Golding S, Sato J, Yokoyama S, Tanaka T, Ignatius S.  Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study. The Lancet Oncology 19, Aug 2014.

Bone HG, Dempster DW, Eisman JA, Greenspan SL, McClung MR, Nakamura T, Papapoulos S, Shih WJ, Rybak-Feiglin A, Santora AC, Verbruggen N, Leung AT, Lombardi A.  Odanacatib for the treatment of postmenopausal osteoporosis: development history and design and participant characteristics of LOFT, the Long-Term Odanacatib Fracture Trial.  Osteoporosis International. 29 Nov 2014.

Quittner AL, Marciel KK, Salathe MA, O’Donnell AE, Gotfried MH, Ilowite JS, Metersky ML, Flume PA, Lewis SA, McKevitt M, Montgomery AB, O’Riordan TG, Barker AF. A preliminary Quality of Life Questionnaire-Bronchiectasis: A patient-reported outcome measure for bronchiectasis. Chest. 2014. doi:10.1378/chest.13-1891.

Solomon DH, Diem SJ, Ruppert K, Lian Y, Liu C, Wohlfart A, Greendale GA, Finkelstein JS. Bone Mineral Density Changes Among Women Initiating Proton Pump Inhibitors or H2 Receptor Antagonists: A SWAN Cohort Study. JBMR 17, AUG 2014.

Zimran A, Gonzalez-Rodriguez DE, Abrahamov A, Elstein D, Paz A, Brill-Almon E, Chertkoff R.  Safety and efficacy of two dose levels of taliglucerase alfa in pediatric patients with Gaucher disease.  Blood Cells, Molecules, and Diseases.  Volume 54, Issue 1, January 2015, Pages 9–16.

Flinn IW, Richard van der Jagt R, Kahl BS, Wood P, Hawkins TE, MacDonald D, Hertzberg M, Kwan Y, Simpson D, Craig M, Kolibaba K, Issa S, Clementi R, Hallman DM, Munteanu M, Chen L, Burke JM. Open-label, randomized, noninferiority study of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of advanced indolent NHL or MCL: the BRIGHT study. Blood March 3, 2014. Published online before print March 3, 2014, doi: 10.1182/blood-2013-11-531327.

Carolan BJ, Hughes G, Morrow J, Hersh CP, O’Neal WK, Rennard S, Pillai SG, Belloni P, Cockayne D, Comellas AP, Han M, Zemans RL, Kechris K and Bowler RP.  The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes.  Respiratory Research 2014, 15:127.

Behrens F, Tak PP, Østergaard M, Stoilov R, Wiland P, Huizinga TW, Berenfus VY, Vladeva S, Rech J, Rubbert-Roth A, Korkosz M, Rekalov D, Zupanets IA, Ejbjerg BJ, Geiseler J, Fresenius J, Korolkiewicz RP, Schottelius AJ, Burkhardt H. MOR103, a human monoclonal antibody to granulocyte–macrophage colony-stimulating factor, in the treatment of patients with moderate rheumatoid arthritis: results of a phase Ib/IIa randomised, double-blind, placebo-controlled, dose-escalation trial. Ann Rheum Dis annrheumdis-2013-204816Published Online First: 17 February 2014 doi:10.1136/annrheumdis-2013-204816.

Poole KES, Treece GM, Gee AH, Brown JP, McClung MR, Wang A, Libanati C. Denosumab Rapidly Increases Cortical Bone in Key Locations of the Femur: A 3D Bone Mapping Study in Women with Osteoporosis. JBMR 2014. DOI: 10.1002/jbmr.2325

M. Dohm, C.M. Black, A. Dacre, J.B. Tillman, G. Fueredi, on behalf of the KAVIAR investigators.  A Randomized Trial Comparing Balloon Kyphoplasty and Vertebroplasty for Vertebral Compression Fractures due to Osteoporosis.  AJNR Am J Neuroradiol, October 2014.

Flinn IW, van der Jagt R, Kahl BS, Wood P, Hawkins TE, MacDonald D, Hertzberg M, Kwan YL, Simpson D, Craig M, Kolibaba K, Issa S, Clementi R, Hallman DM, Munteanu M, Chen L, Burke JM.  Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study. May 8, 2014; Blood: 123 (19).

Eastell R, Boonen S, Cosman F, Reid IR, Palermo L, Cummings SR, Black DM.  Relationship Between Pre-treatment Rate of Bone Loss and Bone Density Response to Once-Yearly ZOL: HORIZON-PFT Extension Study. J Bone Miner Res.  2014.

Sugimoto T, Matsumoto T, Hosoi T, Miki T, Gorai I, Yoshikawa H, Tanaka Y, Tanaka S, Fukunaga M, Sone T, Nakano T, Ito M, Matsui S, Yoneda T, Takami H, Watanabe K, Osakabe T, Okubo N, Shiraki M, Nakamura T.  Three-year denosumab treatment in postmenopausal Japanese women and men with osteoporosis: results from a 1-year open-label extension of the Denosumab Fracture Intervention Randomized Placebo Controlled Trial (DIRECT).  Osteoporosis International.  18 Nov 2014.

Fitzpatrick LA, Wooddell M, Dabrowski CE, Cicconetti G, Gordon DN.  Bone mineral density changes following discontinuation of ronacaleret treatment: Off-treatment extension of a randomized, dose-finding phase II trial.  Bone, Published Online: May 01, 2014.


Sugiyama A, Hashimoto H, Nakamura Y, Fujita T, Kumagai Y. (2013), QT/QTc Study Conducted in Japanese Adult Healthy Subjects: A Novel Xanthine Oxidase Inhibitor Topiroxostat Was Not Associated With QT Prolongation. Journal of Clinical Pharma. doi: 10.1002/jcph.226

Hoy, J., Grund, B., Roediger, M., Ensrud, K. E., Brar, I., Colebunders, R., Castro, N. D., Johnson, M., Sharma, A., Carr, A. and for the INSIGHT SMART Body Composition Substudy Group (2013), Interruption or deferral of antiretroviral therapy reduces markers of bone turnover compared with continuous therapy: The SMART body composition substudy. J Bone Miner Res, 28: 1264–1274. doi: 10.1002/jbmr.1861

Selmaj K, Li DK, Hartung HP, Hemmer B, Kappos L, Freedman MS, Stüve O, Rieckmann P, Montalban X, Ziemssen T, Auberson LZ, Pohlmann H, Mercier F, Dahlke F, Wallström E. Siponimod for patients with relapsing-remitting multiple sclerosis (BOLD): an adaptive, dose-ranging, randomised, phase 2 study. Lancet Neurol. 2013 Jun 11.

Cefalu WT, Leiter LA, Yoon KH, Arias P, Niskanen L, Xie J, Balis DA, Canovatchel W, Meininger G. Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial. Lancet. 2013 Sep 14;382(9896):941-50. doi: 10.1016/S0140-6736(13)60683-2. Epub 2013 Jul 12. PMID: 23850055

Graffagnino C, Bergese S, Love J, Schneider D, Lazaridis C, LaPointe M, Lee K, Lynch G, Hu M, Williams GC. Clevidipine Rapidly and Safely Reduces Blood Pressure in Acute Intracerebral Hemorrhage: The ACCELERATE Trial.  Cerebrovasc Dis 2013;36:173-180 (DOI:10.1159/000351149)

Ringelstein EB, Thijs V, Norrving B, Chamorro A, Aichner F, Grond M, Saver J, Laage R, Schneider A, Rathgeb F, Vogt G, Charissé G, Fiebach JB, Schwab S, Schäbitz WR, Kollmar R, Fisher M, Brozman M, Skoloudik D, Gruber F, Leal JS, Veltkamp R, Köhrmann M, Berrouschot J; for the AXIS 2 Investigators. Granulocyte Colony-Stimulating Factor in Patients With Acute Ischemic Stroke: Results of the AX200 for Ischemic Stroke Trial. Stroke. 2013 Aug 20. [Epub ahead of print] PMID: 23963331

Chawla S, Henshaw R, Seeger L, Choy E, Blay JY, Ferrari S, Kroep J, Grimer R, Reichardt P, Rutkowski P, Schuetze S, Skubitz K, Staddon A, Thomas D, Qian Y, Jacobs I. Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: interim analysis of an open-label, parallel-group, phase 2 study. Lancet Oncol. 2013 Aug;14(9):901-8. doi: 10.1016/S1470-2045(13)70277-8. Epub 2013 Jul 16. PMID: 23867211.

Barras CD, Tress BM, Christensen S, Collins M, Desmond PM, Skolnick BE, Mayer SA, Davis SM; for the Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators.  Quantitative CT Densitometry for Predicting Intracerebral Hemorrhage Growth.  AJNR Am J Neuroradiol. 2013 Jan 10. [Epub ahead of print].  PubMed PMID: 23306009.

Wintermark M, Albers GW, Broderick JP, Demchuk AM, Fiebach JB, Fiehler J, Grotta JC, Houser G, Jovin TG, Lees KR, Lev MH, Liebeskind DS, Luby M, Muir KW, Parsons MW, Kummer RV, Wardlaw JM, Wu O, Yoo AJ, Alexandrov AV, Alger JR, Aviv RI, Bammer R, Baron JC, Calamante F, Campbell BCV, Carpenter TC, Christensen S, Copen WA, Derdeyn CP, Haley EC, Khatri P, Kudo K, Lansberg MG, Latour LL, Lee TY, Leigh R, Lin W, Lyden P, Mair G, Menon BK, Michel P, Mikulik R, Nogueira RG, Østergaard L, Pedraza S, Riedel CH, Rowley HA, Sanelli PC, Sasaki M, Saver JL, Schaefer PW, Schellinger PD, Tsivgoulis G, Wechsler LR, White PM, Zaharchuk G, Zaidat OO, Davis SM, Donnan GA, Furlan AJ, Hacke W, Kang DW, Kidwell C, Thijs VN, Thomalla G, Warach SJ. Acute Stroke Imaging Research Roadmap II. 2013, 16 July. Print ISSN: 0039-2499. Online ISSN: 1524-4628.

Meirhaeghe JV, Bastian L, Boonen S, Ranstam J, Tillman JB, Wardlaw D. A Randomized Trial of Balloon Kyphoplasty and Nonsurgical Management for Treating Acute Vertebral Compression Fractures. SPINE Volume 38, Number 12, pp 971–983. 2013, Lippincott Williams & Wilkins.

Righart R, Duering M, Gonik M, Jouvent E, Reyes S, Hervé D, Chabriat H, Dichgans M. Impact of regional cortical and subcortical changes on processing speed in cerebral small vessel disease. NeuroImage: Clinical 2 (2013) 854–861.

Rini BI, Bellmunt J, Clancy J, Wang K, Niethammer AG, Hariharan S, Escudier B. Randomized Phase III Trial of Temsirolimus and Bevacizumab Versus Interferon Alfa and Bevacizumab in Metastatic Renal Cell Carcinoma: INTORACT Trial.  J Clin Oncol. 2013 Dec 2. [Epub ahead of print]. PubMed PMID: 24297945.

Mease PJ, Gladman DD, Papp KA, Khraishi MM, Thaçi D, Behrens F, Northington R, Fuiman J, Bananis E, Boggs R, Alvarez D. Prevalence of rheumatologist-diagnosed psoriatic arthritis in patients with psoriasis in European/North American dermatology clinics. J Am Acad Dermatol. 2013 Aug 24. pii: S0190-9622(13)00777-9. doi: 10.1016/j.jaad.2013.07.023. [Epub ahead of print] PMID: 23981683


Heilbraun, J. "Blood Pressure as a Cardiac Safety Endpoint: Practical Considerations for Blood Pressure Evaluation in Oncology Research."

Zaidat OO, Castonguay AC, Fitzsimmons BF, Woodward BK, Wang Z, Killer-Oberpfalzer M, Wakhloo A, Gupta R, Kirshner H, Eliasziw M, Thomas Megerian J, Shetty S, Yoklavich Guilhermier M, Barnwell S, Smith WS, Gress DR; VISSIT Trial Investigators. Design of the Vitesse Intracranial Stent Study for Ischemic Therapy (VISSIT) Trial in Symptomatic Intracranial Stenosis. J Stroke Cerebrovasc Dis. 2012 Dec 21. doi:pii: S1052-3057(12)00365-5. 10.1016/j.jstrokecerebrovasdis.2012.10.021. [Epub ahead of print] PMID: 23261207

Freymann, J. B., J. S. Kirby, J. H. Perry, D. A. Clunie and C. C. Jaffe (2012). "Image data sharing for biomedical research—meeting HIPAA requirements for de-identification." Journal of Digital Imaging 25(1): 14–24.

Samaille T, Fillon L, Cuingnet R, Jouvent E, Chabriat H, Dormont D, Colliot O, Chupin M. Contrast-based fully automatic segmentation of white matter hyperintensities: method and validation. PLoS One. 2012;7(11):e48953. doi: 10.1371/journal.pone.0048953. Epub 2012 Nov 12. PubMed PMID: 23152828.

Stolk, J., R. A. Stockley, et al. (2012). "Randomized controlled trial for emphysema with a selective agonist of the gamma type retinoic acid receptor." Eur Respir J. 2012 Jan 26. [Epub ahead of print]

Weidemann, F., Rummey, C., Bijnens, B., Störk, S., Jasaityte, R., Dhooge, J., Baltabaeva, A., Sutherland, G., Schulz, J., Meier, T. (2012) "The Heart in Friedreich Ataxia".

Douglas, P. S., J. J. Carr, M. D. Cerqueira, J. E. Cummings, T. C. Gerber, D. Mukherjee and A. J. Taylor (2012). "Developing an Action Plan for Patient Radiation Safety in Adult Cardiovascular Medicine Proceedings from the Duke University Clinical Research Institute/American College of Cardiology Foundation/American Heart Association Think Tank Held on February 28, 2011." Journal of the American College of Cardiology 59(20): 1833–1847.

Sims E, Garnett S, Guzman F, Paris F, Sultan C, Eugster E. Fulvestrant treatment of precocious puberty in girls with McCune-Albright syndrome. International Journal of Pediatric Endocrinology 2012, 2012:26.

Sharma, A. M., G. Bakris, J. M. Neutel, T. W. Littlejohn, M. Kobe, N. Ting and L. Ley (2012). "Single-pill combination of telmisartan/amlodipine versus amlodipine monotherapy in diabetic hypertensive patients: an 8-week randomized, parallel-group, double-blind trial." Clinical Therapeutics 34(3): 537–551.

Carrié D, Berland J, Verheye S, Hauptmann KE, Vrolix M, Violini R, Dibie A, Berti S, Maupas E, Antoniucci D, Schofer J. A Multicenter Randomized Trial Comparing Amphilimus- With Paclitaxel-Eluting Stents in De Novo Native Coronary Artery Lesions. J Am Coll Cardiol.

Cheriyan, J., S. Kim, L. J. Wolansky, S. D. Cook and D. Cadavid (2012). "Impact of inflammation on brain volume in multiple sclerosis." Archives of neurology 69(1): 82

Düsing, Rainera; Brunel, Patrickb; Baek, InYoungb; Baschiera, Fabiob. Sustained Decrease in Blood Pressure Following Missed Doses of Aliskiren or Telmisarten: the Assertive Double-Blind Randomized Study. Journal of Hypertension, May 2012 - Volume 30 - Issue 5.

Takeuchi T, Harigai M, Tanaka Y, Yamanaka H, Ishiguro N, Yamamoto K, Miyasaka N, Koike T, Kanazawa M, Oba T, Yoshinari T, Baker D. Golimumab monotherapy in Japanese patients with active rheumatoid arthritis despite prior treatment with disease-modifying antirheumatic drugs: results of the phase 2/3, multicentre, randomised, double-blind, placebo-controlled GO-MONO study through 24 weeks. Ann Rheum Dis annrheumdis-2012-201796: 14 September 2012.

Pro, B., R. Advani, P. Brice, N. L. Bartlett, J. D. Rosenblatt, T. Illidge, J. Matous, R. Ramchandren, M. Fanale and J. M. Connors (2012). "Brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large-cell lymphoma: results of a phase II study." Journal of Clinical Oncology 30(18): 2190–2196.

Annamaria Colao, M.D., Ph.D., Stephan Petersenn, M.D., John Newell-Price, M.D., Ph.D., James W. Findling, M.D., Feng Gu, M.D., Mario Maldonado, M.D., Ulrike Schoenherr, Dipl.-Biol., David Mills, M.Sc., Luiz Roberto Salgado, M.D., and Beverly M.K. Biller, M.D., for the Pasireotide B2305 Study Group. A 12-Month Phase 3 Study of Pasireotide in Cushing’s Disease. The New England Journal of Medicine, (ISSN 0028-4793) Vol. 366:914-924 (March 8, 2012).

Drier A, Tourdias T, Attal Y, Sibon I, Mutlu G, Lehéricy S, Samson Y, Chiras J, Dormont D, Orgogozo JM, Dousset V, Rosso C. Prediction of Subacute Infarct Size in Acute Middle Cerebral Artery Stroke: Comparison of Perfusion-weighted Imaging and Apparent Diffusion Coefficient Maps. Radiology. 2012 Aug 24.

Pérez-Cano, R., J. J. Vranckx, et al. (2012). "Prospective trial of Adipose-Derived Regenerative Cell (ADRC)-enriched fat grafting for partial mastectomy defects: The RESTORE-2 trial." European Journal of Surgical Oncology (EJSO).

Carr, J. J., F. M. D. Cerqueira, F. J. E. Cummings, T. C. Gerber and F. D. Mukherjee (2012). "Developing an Action Plan for Patient Radiation Safety in Adult Cardiovascular Medicine."

Harrington K, Berrier A, Robinson M, Remenar E, Housset M, de Mendoza FH, Fayette J, Mehanna H, El-Hariry I, Compton N, Franklin N, Biswas-Baldwin N, Lau M, Legenne P, Kumar R. Randomised Phase II study of oral lapatinib combined with chemoradiotherapy in patients with advanced squamous cell carcinoma of the head and neck: Rationale for future randomised trials in human papilloma virus-negative disease. Eur J Cancer. 2012 Dec 19. doi:pii: S0959-8049(12)00919-7. 10.1016/j.ejca.2012.11.023. [Epub ahead of print] PMID: 23265705


Berenson, J, Pflugmacher R, Jarzem P, Zonder J, Schechtman K, Tillman JB, Bastian L, Ashraf T, Vrionis F. "Balloon kyphoplasty versus non-surgical fracture management for treatment of painful vertebral body compression fractures in patients with cancer: a multicentre, randomised controlled trial." The lancet oncology. 2011. 12(3): 225-235.

Ari Zimran, Einat Brill-Almon, Raul Chertkoff, Milan Petakov, Francisco Blanco-Favela, Eduardo Terreros Muñoz, Sergio E. Solorio-Meza, Dominick Amato, Gloria Duran, Fiorina Giona, Rene Heitner, Hanna Rosenbaum, Pilar Giraldo, Atul Mehta, Glen Park, Mici Phillips, Deborah Elstein, Gheona Altarescu, Mali Szleifer, Sharon Hashmueli, and David Aviezer. Pivotal trial with plant cell–expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease. Blood. 2011;118(22):5767-5773.

Perlman, E. S. (2011). "Imaging CRO Perspective on Quantitative Imaging Measurements" Imaging.

D. Pearson, B. Horton, D. J. Green, Cross calibration of Hologic QDR2000 and GE lunar prodigy for whole body bone mineral density and body composition measurements. J Clin Densitom. 2011 Jul-Sep;14(3):294-301. Epub 2011 May 19. PMID:21600823


Borradaile, K., R. Ford, M. O'Neal and K. Byrne (2010). "Discordance between BICR readers".

Ward LM, Rauch F, Whyte MP, D'Astous J, Gates PE, Grogan D, Lester EL, McCall RE, Pressly TA, Sanders JO, Smith PA, Steiner RD, Sullivan E, Tyerman G, Smith-Wright DL, Verbruggen N, Heyden N, Lombardi A, Glorieux FH. Alendronate for the Treatment of Pediatric Osteogenesis Imperfecta: A Randomized Placebo-Controlled Study. J Clin Endocrinol Metab. 2010 Nov 24. PMID: 21106710


Grund B, Peng G, Gibert CL, Hoy JF, Isaksson RL, Shlay JC, Martinez E, Reiss P, Visnegarwala F, Carr AD; INSIGHT SMART Body Composition Substudy Group. Continuous antiretroviral therapy decreases bone mineral density. AIDS. 2009 Jul 31;23(12):1519-29. PMID:19531929


de Borst GJ, Meijer R, Lo RH, Vosmeer H W G, Ackerstaff R G A, Moll F L. Effect of Carotid Angioplasty and Stenting on Duplex Velocity Measurements in Porcine Model. Journal of Endovascular Therapy. 2008 Dec;15(6):672-9. PMID: 19090631


Keaveny TM, Donley DW, Hoffmann PF, Mitlak BH, Glass EV, San Martin JA (Acknowledgement Bio-Imaging Technologies). Effects of Teriparstide and Alendronate on Vertebral Strength as Assessed by Finite Element Modeling of QCT Scans in Women With Osteoporosis. Journal of Bone and Mineral Research. 2007 Jan;22(1):149-57. PMID: 17042738


Reid DM, Hosking D, Kendler D, Brandi ML, Wark JD, Weryha G, Marques-Neto JF, Gaines KA, Verbruggen N, Melton ME, (Acknowledgement Bio-Imaging Technologies). Alendronic Acid Produces Greater Effects than Risedronic Acid on Bone Density and Turnover in Postmenopausal Women with Osteoporosis. Clinical Drug Investigation. 2006;26(2):63-74. PMID: 17163237

Ripa RS, Jorgensen E, Wang Y, Thune JJ, Nilsson JC, Søndergaard L, Johnsen HE, Køber L, Grande P, Kastrup J, (Acknowledgement Bio-Imaging Technologies). Stem Cell Mobilization Induced by Subcutaneous Granulocyte-Colony Stimulating Factor to Improve Cardiac Regeneration After Acute ST-Elevation Myocardial Infarction. Circulation. 2006 Apr 25;113(16):1983-92. PMID: 16531621

Ripa RS, Wang Y, Jørgensen E, Johnsen HE, Hesse B, Kastrup J, (Acknowledgement Bio-Imaging Technologies). Intramyocardial injection of vascular endothelial growth factor-A165 plasmid followed by granulocyte-colony stimulating factor to induce angiogenesis in patients with severe chronic ischemic heart disease. European Heart Journal. 2006 Aug;27(15):1785-92. PMID: 16825290

Bonnick S, Saag KG, Kiel DP, McClung M, Hochberg M, Burnett SM, Sebba A, Kagan R, Chen E, Thompson DE, de Papp AE, (Acknowledgement Bio-Imaging Technologies). Comparison of Weekly Treatment of Postmenopausal Osteoporosis with Alendronate Versus Risedronate Over Two Years. Journal of Clinical Endocrinology & Metabolism. 2006 Jul;91(7):2631-7. PMID: 16636120

McClung MR, Lewiecki EM, Cohen SB, Bolognese MA, Woodson GC, Moffett AH, Peacock M, Miller PD, Lederman SN, Chesnut CH, Lain D, Kivitz AJ, Holloway DL, Zhang C, Peterson MC, Bekker PJ; AMG 162 Bone Loss Study Group. Denosumab in Postmenopausal Women with Low Bone Mineral Density. The New England Journal of Medicine. 2006 Feb 23;354(8):821-31. PMID: 16495394


Berthiaume MJ, Raynauld JP, Martel-Pelletier J, Labonté F, Beaudoin G, Bloch DA, Choquette D, Haraoui B, Altman RD, Hochberg M, Meyer JM, Cline GA, Pelletier JP. Meniscal Tear and Extrusion are Strongly Associated with the Progression of Knee Osteoarthritis as Assessed by Quantitative Magnetic Resonance Imaging. Annals of the Rheumatic Disease. 2005 Apr;64(4):556-63. PMID: 15374855

Chung KY, Shia J, Kemeny NE, Shah M, Schwartz GK, Tse A, Hamilton A, Pan D, Schrag D, Schwartz L, Klimstra DS, Fridman D, Kelsen DP, Saltz LB. Cetuximab Show Activity in Colorectal Cancer Patients with Tumors that do not Express the Epidermal Growth Factor Receptor by Immunohistochemistry. American Society of Clinical Oncology. 2005 Mar 20;23(9):1803-10. PMID: 15677699


van der Heijde D, Landewé R, Klareskog L, Rodríguez-Valverde V, Settas L, Pedersen R, Fatenejad S, (Acknowledgement Bio-Imaging Technologies). Presentation and analysis of data on radiographic outcome in clinical trials: experience from the TEMPO study. Arthritis and Rheumatism. 2005 Jan;52(1):49-60. PMID: 15641062

Luckey M, Kagan R, Greenspan S, Bone H, Kiel RD, Simon J, Sackarowitz J, Palmisano J, Chen E, Petruschke RA, de Papp AE. Once-weekly alendronate 70 mg and raloxifene 60 mg daily in the treatment of postmenopausal osteoporosis. Menopause. 2004 Jul-Aug;11(4):405-15. PMID: 15243278

Kondagunta GV, Drucker B, Schwartz L, Bacik J, Marion S, Russo P, Mazumdar M, Motzer RJ. Phase II Trial of Bortezomib for Patients with Advanced Renal Cell Carcinoma. Journal of Clinical Oncology. 2004 Sept 15;22(18):3720-5. PMID: 15365068

Raynauld JP, Martel-Pelletier J, Berthiaume MJ, Labonté F, Beaudoin G, de Guise JA, Bloch DA, Choquette D, Haraoui B, Altman RD, Hochberg MC, Meyer JM, Cline GA, Pelletier JP. Quantitative Magnetic Resonance Imaging Evaluation of Knee Osteoarthritis Progression Over Two Years and Correlation with Clinical Symptoms and Radiologic Changes. Arthritis and Rheumatism. 2004 Feb;50(2):476-87. PMID: 14872490

Zhao B, Schwartz LH, Moskowitz CS, Wang L, Ginsberg MS, Cooper CA, Jiang L, Kalaigian JP. Pulmonary Metastases: Effect of CT Section Thickness on Measurement--Initial Experience. Radiology. 2005 Mar; 234(3);934-9. PubMed ID: 15681690

Sebba AI, Bonnick SL, Kagan R, Thompson DE, Skalky CS, Chen E, de Papp AE; Fosamax Actonel Comparison Trial investigators. Response to Therapy with Once-Weekly Alendronate 70 mg Compared to Once-Weekly Risedronate 35 mg in the Treatment of Postmenopausal Osteoporosis. Current Medical Research and Opinion. 2004 Dec;20(12):2031-41. PMID: 15706659

Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, Skolnick BE, Steiner T, (Acknowledgement Bio-Imaging Technologies). Recombinant activated factor VII for acute intracerebral hemorrhage. The New England Journal of Medicine 2005 Feb 25, 352(8):777-85. PMID: 15728810


Kauffmann C, Gravel P, Godbout B, Gravel A, Beaudoin G, Raynauld JP, Martel-Pelletier J, Pelletier JP, de Guise JA. Computer-aided Method for Quantification of Cartilage Thickness and Volume Changes Using MRI: Validation Study Using a Synthetic Model. IEEE Transactions on Biomedical Engineering. 2003 Aug;50(8):978-88. PMID: 12892325

Raynauld JP, Kauffmann C, Beaudoin G, Berthiaume MJ, de Guise JA, Bloch DA, Camacho F, Godbout B, Altman RD, Hochberg M, Meyer JM, Cline G, Pelletier JP, Martel-Pelletier J. Reliability of a Quantification Imaging System Using Magnetic Resonance Images to Measure Cartilage Thickness and Volume in Human Normal and Osteoarthritic Knees. Osteoarthritis Cartilage. 2003 May;11(5):351-60. PMID: 12744941


Drotman MB, Machnicki SC, Schwartz LH, Winston CB, Yoo HH, Panicek DM. Breast Cancer: Assessing the Use of Routine Pelvic CT in Patient Evaluation. American Journal of Roentgenology. 2001 Jun;176(6):1433-6. PMID: 11373208


Schwartz LH, Ginsberg MS, DeCorato D, Rothenberg LN, Einstein S, Kijewski P, Panicek DM. Evaluation of Tumor Measurements in Oncology: Use of Film-Based and Electronic Techniques. Journal of Clinical Oncology. 2000 May;18(10):2179-84. PMD: 10811683