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Chahin Pachai

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Chahin Pachai, Ph.D.
Vice President and Executive Director, Lyon

Dr. Chahin Pachai obtained a degree in Electrical and Electronic Engineering from INSA Lyon in 1995, and a Ph.D. in the field of quantitative MRI, image segmentation and CNS diseases in 2000. He was a research fellow at the Surgical Planning Laboratory, Brigham & Women’s Hospital, Harvard Medical School (1997-98). After attending business and management courses at Ecole Management de Lyon (2001), Chahin founded Theralys in October 2001, an imaging CRO which was acquired by Bio-Imaging Technologies in February 2007. Chahin now manages the BioClinica office based in Lyon, France as Vice President and Executive Director.

Authored Publications

Opherk C, Gonik M, Duering M, Malik R, Jouvent E, Hervé D, Adib-Samii P, Bevan S, Pianese L, Silvestri S, Dotti MT, De Stefano N, Liem M, Boon EM, Pescini F, Pachai C, Bracoud L, Müller-Myhsok B, Meitinger T, Rost N, Pantoni L, Oberstein SL, Federico A, Ragno M, Markus HS, Tournier-Lasserve E, Rosand J, Chabriat H, Dichgans M. Genome-Wide Genotyping Demonstrates a Polygenic Risk Score Associated With White Matter Hyperintensity Volume in CADASIL. Stroke. 2014 Feb 27. [Epub ahead of print]

Wyman BT, Harvey DJ, Crawford K, Bernstein MA, Carmichael O, Cole PE, Crane PK, Decarli C, Fox NC, Gunter JL, Hill D, Killiany RJ, Pachai C, Schwarz AJ, Schuff N, Senjem ML, Suhy J, Thompson PM, Weiner M, Jack CR Jr. Standardization of analysis sets for reporting results from ADNI MRI data. Alzheimer’s Disease Neuroimaging Initiative. Alzheimers Dement. 2012 Oct 27. doi:pii: S1552-5260(12)02379-5. 10.1016/j.jalz.2012.06.004. Epub 2012 Oct 27. PMID: 23110865

Coric V, van Dyck CH, Salloway S, Andreasen N, Brody M, Richter RW, Soininen H, Thein S, Shiovitz T, Pilcher G, Colby S, Rollin L, Dockens R, Pachai C, Portelius E, Andreasson U, Blennow K, Soares H, Albright C, Feldman HH, Berman RM. Safety and Tolerability of the γ-Secretase Inhibitor Avagacestat in a Phase 2 Study of Mild to Moderate Alzheimer Disease. Archives of Neurology 2012 Aug 13:1-12

Duering M, Zieren N, Hervé D, Jouvent E, Reyes S, Peters N, Pachai C, Opherk C, Chabriat H, Dichgans M. Strategic role of frontal white matter tracts in vascular cognitive impairment: a voxel-based lesion-symptom mapping study in CADASIL. Brain. 2011 Aug;134(Pt 8):2366-75. Epub 2011 Jul 14

Nonent M, Ben Salem D, Serfaty JM, Buthion V, Pasco-Papon A, Rotaru C, Bressollette L, Papon X, Pachai C, Fortrat JO, Gouny P, Badra A, Berge J, Le Bras Y, Cottier JP, Gauvrit JY, Douek P. Overestimation of moderate carotid stenosis assessed by both Doppler US and contrast enhanced 3D-MR angiography in the CARMEDAS study. J Neuroradiol. 2011 Jul;38(3):148-55. Epub 2010 Aug 21.

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