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Case Studies

Recruitment

Alzheimer's Disease

Challenge:

Recruit and retain patients for a global study investigating a potential new treatment for Alzheimer's.

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Pediatric Schizophrenia

Challenge:

Recruit children with schizophrenia, ages 13-17, for an FDA-mandated pediatric clinical study to evaluate an adult-approved medication for treatment of children with schizophrenia.

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Chronic Pain Study

Challenge:

Patient recruitment, patient retention, and study coordinator site support to:

  • Motivate 55+ seniors to actively participate in a clinical study with a significant study burden – 3 endoscopies and a 7-month time commitment.
  • Communicate key benefits of study participation.
  • Keep study top of mind with local site study staff.

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Retention

RAPSODI Study

Challenge:

Develop a comprehensive patient retention program to support both subjects and sites in a three-year, placebo-controlled, US-based study, with specific goals of reducing the 23% drop-out rate prior to program-launch and fostering compliance to this generally non-compliant population over the course of three years.

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ALLEGRO Study

Challenge:

Develop a customized patient retention program that could be implemented swiftly to support sites in retaining patients over frequent study visits.

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The ALFACHIN Study

Challenge:

Develop and localize study and patient retention materials quickly at significant cost savings for a global study for severely-afflicted patients. Specific goals included:

  • Designing a program that addressed the needs and interests of all pediatric participants.
  • Determining the most appropriate activities for a population coping with various degrees of paralysis.
  • Ensuring that the program was adaptable across multiple cultures and languages.

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Rescue

Childhood Depression Study

Challenge:

Develop new message approach and support materials for a pivotal study which had expensed its recruitment budget with another provider and failed to meet recruitment objectives due to ineffective site support materials.

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Nerve Pain Study

Challenge:

Develop a 'rescue strategy' for a clinical study that was not achieving its subject recruitment and retention objectives. Goals included:

  • Motivating both subjects and local site study staff to study completion.
  • Supporting select study sites through a 'patient advocacy' program directed at local community organizations.

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ADDITIONAL RESOURCES

Patient Recruitment and Retention

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Alzheimer's Disease

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Pediatric Schizophrenia

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Chronic Pain Study

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RAPSODI Study

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ALLEGRO Study

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The ALFACHIN Study

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Childhood Depression Study

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Nerve Pain Study

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Global Clinical Research

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Bioclinica is organized into three business segments so that we can provide expert service and multifaceted technologies. Our Medical Imaging & Biomarkers segment includes an Imaging Core Lab, a Cardiovascular Safety division, and a Molecular Marker Laboratory. Our eHealth segment comprises eClinical Solutions, Randomization & Trial Supply Management, Safety & Regulatory Solutions, and Financial Lifecycle Solutions. Under the Global Clinical Research segment, we offer a network of research sites, patient recruitment, and a Post-Approval Research division.

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