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Adiponectin // Acrp30

Biomarker Therapeutic Areas: 
Biomarker Matrices: 

Adiponectin, also called adipocyte complement-related protein of 30kDa (Acrp30), is a collagen-like protein predominantly synthesized and secreted by adipocytes (Scherer et al., 1995). Adiponectin is the most abundant adipokine in blood and exists under three forms: dimers, hexamers or higher order multimers (respectively called low-, middle-, and high-molecular weight forms) (Pajvani et al., 2003). Among its role in lipid and glucose metabolism regulation, adiponectin is also described for its involvement in inflammatory processes (Ouchi et al., 2011). Reduced serum levels of adiponectin are found in obesity and cardiovascular diseases whereas elevated concentrations can be observed in RA patients (Arita et al., 1999; Liu et al., 2015; Pilz et al., 2006; Urbonaviciene et al., 2010).

Bioclinica Lab employs a manual sandwich ELISA for the measurement of the different forms of Adiponectin in serum.

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