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MPO // Myeloperoxidase

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Myeloperoxidase (MPO) is the peroxidase responsible for the green tinge in pus and phlegm. Named first verdoperoxidase after its isolation from canine pus, MPO is implicated in the defense against ingested pathogens. MPO constitute approximately 5% of the total neutrophil content in protein (Klebanoff et al., 2013). MPO is glycoprotein belonging to the peroxidase-cyclooxygenase superfamily which also includes eosinophil peroxidase, lactoperoxidase and thyroid peroxidase. MPO have an additional sulfonium ion linkage (Carpena et al., 2009).

Bioclinica Lab employs a manual sandwich immunoassay designed for the measurement of MPO in plasma.

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