Please Wait...

OPG // Osteoprotegerin

Biomarker Therapeutic Areas: 
Biomarker Matrices: 

Osteoprotegerin (OPG) is a secretory glycoprotein composed of 401 amino acids (mature form with 380 amino acids) and seven structural domains. OPG exists as a disulfide-linked homodimer or as a monomer (Simonet et al., 1997). OPG belongs to the TNF receptor superfamily and was initially described as a cytokine, binding essentially the Receptor Activator of Nuclear Factor κβ Ligand (RANKL).Since, OPG have been found to be implicated in other pathways (Baud’huin et al., 2013). In addition to its implication in bone metabolism, OPG have been associated with diabetes of types 1 and 2, obesity metabolic syndrome, atherosclerosis and hypertension (Pérez de Ciriza et al., 2015).

Bioclinica Lab employs a manual sandwich immunoassay for the measurement of OPG in serum.

Leader in Clinical Trial
Management Solutions

Successful clinical trials require the ability to see key details and uncover hidden insights. Bioclinica utilizes science and technology to bring clarity to clinical trials, helping companies to develop new life-improving therapies more efficiently and safely.

Ck out best-of-breed trial #technologies & services: #RTSM, #esource, #EDC, site & patient #payments, global site… https://t.co/DJCNZ9C1uq
Bioclinica (Yesterday)
ICYMI: A discussion on recently released FDA draft guidance on assessment of blood pressure response in… https://t.co/7fmrkhhuQd
Bioclinica (Yesterday)
Our CIO & EVP Tech Gavin Nichols adds to #digitaltransformation discussion at #CMAsummit18 : W genomics & precision… https://t.co/oisqWvGJXC
Bioclinica (3 days ago)
Greetings from Tokyo where @bioclinica's Japan. China & US locations R@DrugInfoAssn DIA Japan. Discuss region-spec… https://t.co/HMzmFwA9pm
Bioclinica (5 days ago)
Reminder to join us in a live #Xtalks webinar tomorrow 11/6 on Electronic Data Capture (EDC). Everything clinical t… https://t.co/WS0L3QQnPv
Bioclinica (2 weeks ago)
Meet with representatives of Bioclinica's Japan, China & US locations at DIA Japan. Angel Y., Hidenori Seshimo & Er… https://t.co/j1alTH8oBm
Bioclinica (2 weeks ago)

Latest Blogs:

Dr. Joby John
Transformational Trends in Investigator Site Payments
Clinical Supply Chain Success: Leveraging Technology
Blood pressure monitor
Prescription box
Latin America: Benefit from the Right Partner