Please Wait...

PYD // Pyridinium Crosslinks

Biomarker Therapeutic Areas: 
Biomarker Matrices: 

Pyridinium Crosslinks (PYD) or Pyridinoline is a non-reducible crosslinks of collagen formed during collagen maturation. High levels of PYD are found in cartilage, in comparison with bone levels. PYD crosslinks measured in urine reflect bone resorption (Seibel et al., 1992). In bone, the crosslinks of mature collagen are: PYD and deoxypyridinoline, they are released in circulation and urine during bone resorption (Delmas, 1993). Pyridinoline crosslinks were initially measured with HPLC, but an immunoassay have been developed to allow measurement of PYD without need of HPLC techniques (Seyedin et al., 1993).

Bioclinica Lab employs a manual competitive enzyme-linked immunoassay designed for the measurement of PYD in urine.

Leader in Clinical Trial
Management Solutions

Successful clinical trials require the ability to see key details and uncover hidden insights. Bioclinica utilizes science and technology to bring clarity to clinical trials, helping companies to develop new life-improving therapies more efficiently and safely.

Join Bioclinica in a live #Xtalks webinar 10/31 exploring challenges & benefits of different sourcing models to man…
bioclinica (3 hours ago)
Bioclinica contributions toward advancement of #Alzheimer's disease research & therapies showcased in 8 different s…
bioclinica (9 hours ago)
Bioclinica’s Joby John reflects on the #SCDM2018 Annual Conference & being a part a thriving community of clinical…
bioclinica (Yesterday)
RT @bioclinica: Our own Jeff Heilbraun is in Tokyo nxt wk to lead a discussion at DIA’s Cardiac Safety Workshop in Japan. Jeff will give an…
bioclinica (Yesterday)
RT @Xtalks: Trends in #SitePayments: Insight into How CROs Can Gain a Competitive Edge This webinar will focus on the latest market researc…
bioclinica (Yesterday)
Great connecting w @bioclinica clients Odonate Therapeutics, Eisai, & PCI Biotech, at #ESMO18 #oncology…
bioclinica (Yesterday)

Latest Blogs:

Dr. Joby John
Transformational Trends in Investigator Site Payments
Clinical Supply Chain Success: Leveraging Technology
Blood pressure monitor
Prescription box
Latin America: Benefit from the Right Partner