Please Wait...
Bioclinica delivers therapeutic expertise, regulatory leadership, and global operations to expedite neuroscience clinical trials with imaging endpoints. We have more experience in the design and conduct of neuroscience clinical trials than any other core lab, highlighted by our support of the majority of Phase III Alzheimer's Disease clinical trials incorporating imaging endpoints.
Bioclinica is the world leader in centralized imaging services, providing sponsors with comprehensive support for clinical trials across all major neuroscience indications. We understand the complexities of imaging endpoints required for monitoring specific disease states.
Bioclinica is the world leader in centralized imaging services, providing sponsors with comprehensive support for clinical trials across all major neuroscience indications. We understand the complexities of imaging endpoints required for monitoring specific disease states.
Contact us for more information or to speak with us about how we can support your next trial.
Bioclinica advances clinical trials via SMART — a robust suite of centralized medical imaging services designed to manage the complex imaging process from image receipt to analysis, to regulatory submission.
Advanced medical imaging can provide important, quantitative information on global and regional structural changes in the brain, informing patient eligibility and drug efficacy. Molecular imaging and functional MRI provide increasingly vital information about brain function, enabling sophisticated evaluation of disease states. Our neuroscience team has experience with the latest advancements in biomarkers.
Images are electronically uploaded from trial sites, blinded and rigorously quality checked. Bioclinica employs a “Multi-Step Quality Control” process that ensures the image data received from the sites will be of the highest quality. Our process enables thorough and precise image data management and analysis. We accept DICOM or manufacturer-specific formats.
We maximize your subjects' image data to help achieve the statistical power of your study. The end result is quality measurement data — delivered on time and within budget.
We track all patients enrolled in studies and all imaging data generated during the course of a clinical trial. Our expert technicians use innovative tools to deeply review, update, and assure compliance with clinical trial protocols and defined reading paradigms. This enables queries to be issued, tracked, and resolved. Our ICL collection management process is designed to detect early on any substandard image quality or violations of the imaging protocol.
Our imaging core lab collection management process includes:
Advanced neuroimaging provides sensitive, quantitative and longitudinal information on global and regional structural changes in the brain, informing patient eligibility and drug efficacy of new treatments in clinical trials. Beyond structural data, Molecular imaging (PET) and functional MRI provide clinicians with increasingly sensitive information about brain function, enabling sophisticated evaluation of disease state modifications.
Our neuroscience team has experience with the latest advancements in molecular neuroimaging and biomarkers. Through collaborations with scientists at leading universities, government agencies, and research foundations, Bioclinica continually innovates and develops standardized neuroimaging methodologies for evaluating investigational therapies.
Angiography
ASL-perfusion
CT
CT angiography (CTA)
Diffusion Tensor Imaging (DTI)
Diffusion Weighted Imaging (DWI)
Dopamine Transporter (DaT)
Florbetapir (Amyvid) PET
Fluorodeoxyglucose (FDG) PET
Flutemetamol (Vizamyl) PET
Functional MRI (fMRI)
Magnetic Resonance Angiography (MRA)
Magnetization Transfer (MTR)
Perfusion Weighted Imaging (PWI)
Pittsburgh compound (11C-PiB) PET
SPECT (DaTscan, In-111 labeled tracers)
Susceptibility Weighted Imaging (SWI)
Volumetric MRI
Bioclinica takes careful measures to ensure that the data you receive is of the highest quality and meets regulatory compliance. Initial site authorization and ongoing image quality control impact the overall quality of data emerging from a trial. We maintain close interactions with clinical and imaging sites, helping sponsors identify quality findings, resolve image queries, and adhere to protocol workflow and timelines.
Rigorous site authorization and training
Image QC
Independent eligibility and safety assessments
Robust quantitative analysis
Validated, regulatory compliant software
Neuroscience clinical trials rely on the accurate collection of high quality image data for complex endpoints. Bioclinica's renowned neuroscience team delivers specialized expertise in support of your trial, from protocol design through regulatory submission.
Expert Neuroradiologists
Dedicated Image Processing Scientists
PET specialists
MRI Physicists
Our deep understanding of neuroimaging allows us to assign the most appropriate scientific experts to your study. Under the leadership of Joyce Suhy, PhD, Bioclinica provides extensive knowledge and Neuroscience experience to the design, implementation and conduct of your trial.
Click on a name below to learn more about the members of our Neuroscience team.
Joyce Suhy, PhD
Vice President and Head of Neuroscience
Luc Bracoud, MSc
Director, Neuroscience
Meredith Burke, PhD, PMP,
Director, Project Management
David Scott, PhD
Scientific Director, Neuroscience
Gennan Chen, PhD
Director, Research and Development, Engineering
Joonmi Oh, PhD
Director, Global Imaging Services - Clinical Services Management
Mehul Sampat, PhD
Senior Software Engineer
Joël Schaerer, PhD
Algorithm and Visualization Team Lead, Engineering
Evangelia Kryoneriti, MSc
Software Engineer, Engineering
Jing He, PhD
Software Engineer, Engineering
Kate Adamczuk, PhD
Scientist
Nicolas Pannetier, PhD
Scientist
Beth Gorman, BS CNMT
PET Research Specialist
Maureen Runkle, BS, CNMT, R.T.(N)
PET Research Specialist
Howard Simon, PhD
Senior Scientist
Michael W. Weiner, MD
Senior Scientific Advisor
With Bioclinica, you'll receive powerful, comprehensive reporting services for sites and sponsors, which supports the management and review of data for clinical trials.
Gain access to real-time reports, such as:
Metrics reports
Project status reports
Custom client reports
Analysis results reports
Safety and eligibility reports
Billing reports
Successful clinical trials require the ability to see key details and uncover hidden insights. Bioclinica utilizes science and technology to bring clarity to clinical trials, helping companies to develop new life-improving therapies more efficiently and safely.