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Medical and Diagnostic Imaging Modalities

Bioclinica has extensive experience with medical imaging and diagnostic imaging modalities for clinical trials.
A computerized tomography (CT) scan combines a series of X-ray images taken from different angles and uses computer processing to create cross-sectional images, or slices, of the bones, blood vessels and soft tissues inside your body.
  • CT Angiography (CTA)
  • Cardiac CT
  • CT Enterography (CTE)
  • CT Urography (CTU)
  • Dual-Energy CT (DECT)
  • High Resolution CT (HRCT)
  • Quantitative CT (QCT)
  • High Resolution Peripheral QCT (HR-pQCT)
Dual-energy X-ray absorptiometry (DXA) is most often used to diagnose osteoporosis. The DXA scanner measures the bone mineral density (BMD) and can be used to predict fracture risk. The same scan can measure the fat and lean composition of the body.
  • Bone Mineral Density (BMD)
  • Hip Structural Analysis (HSA)
  • Trabecular Bone Structure (TBS) 
  • Body Composition
Endoscopy is a procedure used in medicine to look inside the body by inserting a camera directly into the body through natural openings or surgical incisions.
  • Colonoscopy & sigmoidoscopy (large intestine)
  • Capsule Endoscopy (GI tract)
  • Enteroscopy (small intestine)
  • Esophagogastroduodenoscopy 
  • Rhinoscopy (nose and sinus) 
  • Bronchoscopy (lower respiratory tract)
  • Laryngoscopy (upper respiratory tract)
  • Laparoscopy (abdominal or pelvic cavity)
  • Arthroscopy (interior of a joint)
Medical photography
Medical photography is the documentation of the clinical presentation of disease or disorders or outcomes of therapeutic interventions.
  • Still images
  • Videography
Magnetic Resonance Imaging (MRI) uses radio waves and magnets to interact with water molecules to form a cross-sectional image of the body, similar to CT. It is particularly useful for imaging the brain, organs, muscles and joints.
  • Arterial Spin Labeling (ASL) Perfusion
  • Cardiac MR (CMR)
  • Diffusion Tensor Imaging (DTI)
  • Diffusion Weighted Imaging (DWI)
  • Dynamic Contrast-Enhanced MRI (DCE-MRI)
  • Free Water Fraction
  • Functional MRI (fMRI), task and task-free
  • Iron Load Quantitative Susceptibility Mapping (QSM)
  • Magnetization Transfer Ratio (MTR)
  • MR Angiography (MRA)
  • MR Cholangiopancreatography (MRCP)
  • MR Elastography (MRE)
  • MR Enterography (MREn) 
  • MR Spectroscopy (MRS)
  • Neuromelanin
Molecular Imaging
Molecular Imaging focuses on imaging molecules of medical interest within living patients by the injection of radioactive tracers into the body and recording the emitted radiation.
  • Positron Emission Tomography (PET)
  • PET/CT
  • PET/MR
  • Single Photon Emission Computed Tomography (SPECT)
  • Planar scintigraphy 
  • Multi-Gated Acquisition Scan (MUGA)
Optical coherence tomography (OCT) is an imaging technique that uses low-coherence light to capture micrometer-resolution, two- and three-dimensional images from within optical scattering media.
  • Time Domain OCT
  • Frequency Domain OCT
  • Full Field OCT
  • OCT Angiography
Ultrasound uses high-frequency sound waves to visualize the internal structures of the body. Special techniques can be used to detect and measure blood flow in vessels and the material properties of tissues.
  • B-Mode and M-Mode
  • Contrast Enhanced Ultrasound (CEUS)
  • Duplex
  • Duplex Doppler
  • Abdominal Ultrasound
  • Intestinal Ultrasound (IUS)
  • Transvaginal Ultrasound (TVU)
  • Elastography
  • Echocardiography
  • Flow Mediated Dilation (FMD)
  • Musculoskeletal Ultrasound (large and small joints)
Radiography uses X-rays to image the internal of the body in particular the bones and joints. Liquids that absorb X-rays may be injected into the body to visualize the vascular system and other structures.
  • General
  • Mammography
  • Angiography
  • Quantitative Coronary Angiography (QCA)
  • Ventriculography
EKG - cardiogram for monitoring heart beat. 3D rendered illustration.

Want to learn more about how Bioclinica’s medical and diagnostic imaging modalities solutions can benefit your clinical studies?